Hepatitis C


  • Almost all patients can be successfully cured with direct-acting antiviral (DAA) therapy.
  • Populations at risk include: people with current or history of injecting drug use; previous incarceration; born in hepatitis C virus (HCV) endemic countries and regions; received blood products before 1990 or in developing countries; engage in condomless anal sex with a partner with HCV infection, participate in group sex and current HIV pre-exposure prophylaxis (PrEP) use (See Hepatitis Australia - hepatitisaustralia.com).
  • Hepatitis C may cause acute hepatitis (uncommon).
  • Chronic HCV is defined as a HCV VL detected in the absence of clinical features of acute hepatitis infection. 
  • Disease progression is usually slow but may cause cirrhosis, liver failure and hepatocellular carcinoma.
  • Disease progression can be affected by age at infection, duration of infection, alcohol and other drug use, co-infection with HIV or hepatitis B virus (HBV), male gender, stage of fibrosis and higher alanine aminotransferase (ALT) levels, other comorbid conditions e.g. diabetes.
  • Almost all patients can be successfully treated with direct-acting antiviral (DAA) therapy.
  • Ensure your patient uses new equipment if they continue to inject drugs.